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Impact of GFP Overexpression on CHO Cell Metabolic Phenotype Alongside a Gene of Interest in an IgG-producing CHO Cell Line

Construction of plasmid to investigate the impact of cumate-inducible overexpression of a gene of interest and green fluorescent protein (GFP) on metabolic efficiency, cell growth, and specific productivity.

Posted by buchanle on Tuesday, April 30th, 2024 in May 2024, , , ,

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Self-regulated Learning and Spelling: A Pilot Study of First Graders

First graders’ self-efficacy and metacognition were measured to assess the development of children’s self-regulated learning abilities.

Posted by buchanle on Tuesday, April 30th, 2024 in May 2024, , ,

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Evaluating Cell Culture Systems for Engulfment Receptor Function: Jedi-1 in BV2 and HeLa Cells

Jedi-1 is not expressed endogenously by BV2 cells; transfection of HeLa cells with Jedi-1 induces engulfment of apoptotic neural cells.

Posted by John Lee on Tuesday, May 30th, 2023 in May 2023, , , ,

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Recalibration and Spatial Recall in an Immersive Virtual Environment

A study of the effects of age and gender of spatial memory in a virtual environment.

Posted by John Lee on Tuesday, May 30th, 2023 in May 2023, , ,

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Defining the Immunogenomics of Allopurinol-Induced SJS/TEN

This study aims to validate the involvement of a known HLA risk allele associated with ALP-SJS/TEN as well as to identify other novel HLA alleles or immune factors associated with disease pathogenesis.

Posted by John Lee on Tuesday, May 30th, 2023 in May 2023, , , , , , , ,

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Breaking Down the Development of Children’s Ordinality Understanding

This paper analyzes the association of various early number skills with the development of numeral ordinality knowledge.

Posted by John Lee on Tuesday, May 30th, 2023 in May 2023, , , ,

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Investigating the Effect of Rock Conditions on Ordovician Fossil Properties in Nashville, Tennessee

Fossils were counted and measured in three local outcrops, and these results were compared to the rock conditions in which they were found in order to assess biases in the fossil record.

Posted by John Lee on Saturday, May 7th, 2022 in May 2022, , , , ,

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Investigating the Differences in Brewing Quality Between Wild and Domestic Yeasts

Through examining the variable fermentation characteristics, the differences between wild and domestic yeasts were determined and analyzed through a commercial brewing perspective.

Posted by John Lee on Saturday, May 7th, 2022 in May 2022, , , , ,

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The Effects of Daily Activities on Depressive Mood in High School Students

This study examines the relationship between screen use, sleep, and physical activity on mental health in high school students.

Posted by John Lee on Saturday, May 7th, 2022 in May 2022, , , ,

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The Effect of Background Music on Standardized Math Test Performance in High School Students

Students were given a math test with or without background music in order to measure its effects on test score and completion time.

Posted by John Lee on Saturday, May 7th, 2022 in May 2022, , ,

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An Analysis of the Relationship Between Stunting and Macronu-trient Intakes on a Global Scale

This study examined the relationship between stunting and macronutrient intakes, including animal protein, plant protein, fat, and car-bohydrates in 117 countries.

Posted by John Lee on Saturday, May 7th, 2022 in May 2022, ,

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Breast Cancer Metastasis to the Bone Microenvironment

A majority of breast cancer patients develop metastases in their bone, and the bone microenvironment plays a large role in recruiting tumor cells from the breast.

Posted by John Lee on Thursday, May 20th, 2021 in May 2021, , , ,

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Liposome-based Strategies to Mitigate Ischemic Stroke-induced Neurodegeneration

Liposome-based drug delivery to the brain is a well-established and an effective approach for delivering neuroprotectants across the BBB in ischemic stroke.

Posted by John Lee on Thursday, May 20th, 2021 in May 2021, , , ,

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Removing Dark Region Artifacts using Deep Neural Networks with a Hyperparameter Search

This study used deep neural networks to remove dark region artifacts in order to create clearer ultrasound images.

Posted by John Lee on Wednesday, May 19th, 2021 in May 2021, , ,

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Radiation Emissions of Primordial Black Holes as Dark Matter in a Dwarf Galaxy

Dark matter in a simulated dwarf galaxy was replaced with primordial black holes and the resulting radiation is analyzed.

Posted by John Lee on Thursday, December 24th, 2020 in May 2018, , ,

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Analyzing the role of endothelial cell derived Jedi-1 in postnatal neurogenesis

Neural stem cells experience a decrease in quiescence in the absence of Jedi-1 positive endothelial cells.

Posted by John Lee on Wednesday, December 23rd, 2020 in May 2020, , , ,

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Feasibility assessment of heat transfer as an independent variable to compare cold exposure studies of brown adipose tissue

A flow-temperature sensing device was incorporated into a water-blanket system to calculate heat transfer for use as an independent varia-ble in cooling studies

Posted by John Lee on Wednesday, December 23rd, 2020 in May 2020, , ,

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Validating a Dual-Threshold Peak Detection for Calcium Signals Around Laser-Induced Epithelial Wounds

A comparison between an automated method of collection calcium peaks to a manual version to determine the accuracy of the automated system and gain insight into the role of calcium during the wound healing process.

Posted by John Lee on Wednesday, December 23rd, 2020 in May 2020, ,

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Analyzing the Spatial Organization of Tuberous Sclerosis Complex Tumor Cells Using Immunostaining and Computational Approaches

Immunostaining and Computational approaches through the HistoCAT software determined a non-random organization of cells in Subependymal Giant-Cell Astrocytomas (SEGAs), a type of Tuberous Sclerosis Complex tumor.

Posted by John Lee on Wednesday, December 23rd, 2020 in May 2020, , ,

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Provenance of Zircon in McMurdo Sound Antarctica

This study analyzes the ages of zircon minerals found in the ANDRILL core in order to track past ice flow.

Posted by John Lee on Wednesday, December 23rd, 2020 in May 2020, , , ,

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Interactive Anatomy and Physiology Augmented Reality Application

An interactive augmented reality prototype application was created as an interactive educational tool for the classroom.

Posted by John Lee on Tuesday, December 22nd, 2020 in May 2019, , , ,

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Utilizing Camera Traps to Analyze Relative Abundance of Basking Turtles in Wetland Ecosystems

Solar irradiance positively influences the time of day at which red-eared sliders bask in wetland ecosystems.

Posted by John Lee on Tuesday, December 22nd, 2020 in May 2019, , , , ,

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Analyzing homozygous loss of TSC2 mutants in human iPSC-derived neural spheres.

Early neural progenitors with tuberous sclerosis are larger and more disorganized than those without.

Posted by John Lee on Tuesday, December 22nd, 2020 in May 2019, , ,

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Using MicroCT to Improve Precision of Uranium-Thorium Dating in Speleothem Records

Avoiding impurities by using microCT to look below stalagmite surfaces leads to more precise age models and better climate records.

Posted by John Lee on Tuesday, December 22nd, 2020 in May 2019, , ,

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Quantifying Young’s Modulus of Gelatin Substrates for in vitro BBB Models

An examination of the effect of gelatin concentration on Young’s Modulus preformed for future in vitro Blood Brain Barrier studies.

Posted by John Lee on Tuesday, December 22nd, 2020 in May 2018, , ,

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Concrete Printing System Construction and Characterization of 3-D Printed Cement-based Materials

Cement-based materials were designed and printed on a novel extrusion system, then characterized.

Posted by John Lee on Tuesday, December 22nd, 2020 in May 2018, , , , ,

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The role of fructose in the expression of extracellular matrix markers and cytokines released by M1 and M2 macrophages that regulate the progression of nonalcoholic fatty liver disease

The role of the sugar fructose on the induction of extracellular matrix proteins and inflammation in polarized macrophages.

Posted by John Lee on Tuesday, December 22nd, 2020 in May 2018, , ,

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Recovery of Putative Temperature-Sensitive Mutations in Coro-navirus Nonstructural Protein 5 Reveals Conserved Determi-nants of nsp5 Structure

This study identifies temperature-sensitive mutations as conserved determinants in coronavirus nsp5 proteins of strains HKU1 and OC43.

Posted by Greta Clinton-Selin on Wednesday, June 28th, 2017 in May 2013, , ,

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Using Detrital Zircon Age Distributions to Corroborate Evidence of Early Holocene Megafloods

Zircon grain age distributions provide information on the origins of early holocene megaflood related sediment.

Posted by Greta Clinton-Selin on Thursday, June 8th, 2017 in May 2017, , , ,

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Development of a Portable and Inexpensive Ultrasound Imaging Device for Use in the Developing World

A portable and inexpensive ultrasound device that could be used in the developing world was developed and tested.

Posted by Greta Clinton-Selin on Thursday, June 8th, 2017 in May 2017, , , ,

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Bulk Mechanical Characterization of Nanoparticle Concrete-Equivalent Mortars

Ultimate concrete strength was studied as a factor of both mass and surface area of nanoparticles added to the material.

Posted by Greta Clinton-Selin on Wednesday, June 7th, 2017 in May 2017, , , , , ,

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Creating an Agent-Based Model to Explore the Spread of Zika Virus

Predicted Zika outbreak severity directly correlates with human population density.

Posted by Greta Clinton-Selin on Tuesday, May 30th, 2017 in May 2017, ,

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POPDC3 Regulates Epithelial-Mesenchymal-Transition in Colorectal Cancer Cells

The POPDC3 protein was identified as a potential regulator of the epithelial-mesenchymal-transition process in colorectal cancer.

Posted by Greta Clinton-Selin on Wednesday, May 24th, 2017 in May 2017, , ,

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Characterization of the Downstream Effects of Apical Mistrafficking of Epiregulin and Potential for Transformation in Polarized Epithelial Cells

Loss of epithelial polarity and mistrafficking of Epiregulin may be a driving force for cancer in polarized epithelial cells.

Posted by Greta Clinton-Selin on Wednesday, June 29th, 2016 in May 2016, , , , ,

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Classification of Infant Cries Using Acoustic Features

Identifying an acoustic feature combination that can accurately differentiate between infant cries.

Posted by Greta Clinton-Selin on Wednesday, June 29th, 2016 in May 2016, , , , , ,

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Determining the Turning Wing Kinematics of a Ruby-Throated Hummingbird

The turning wing kinematics of a ruby-throated hummingbird are determined by use of a blade element model.

Posted by Greta Clinton-Selin on Wednesday, June 8th, 2016 in May 2016, , ,

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Improving Patterned Nanoporous Gold as an Effective Surface Enhanced Raman Scattering Template

An imprinted nanoporous gold substrate was optimized to create a low power Raman biological and chemical sensor.

Posted by Greta Clinton-Selin on Tuesday, June 7th, 2016 in May 2016,

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Regulation of Pro-Inflammatory Phenotypes by Carcinogenic and Non-Carcinogenic Helicobacter pylori strains

In order to quantify H. pylori virulence, the concentration of IL-8 secreted by AGS gastric epithelial cells co-culture with H. pylori strains, isolated from patients with gastritis or gastric adenocarcinoma was measured and compared.

Posted by Greta Clinton-Selin on Thursday, June 2nd, 2016 in May 2016, , , ,

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Effect of NRIF on p75 Expression

NRIF may be a transcriptional repressor of p75 expression.

Posted by Greta Clinton-Selin on Tuesday, October 20th, 2015 in May 2014, , , ,

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IL-6 Secreted from Pancreatic Stellate Cells Activates STAT3 and Promotes Cell Growth and Invasive Ability of Pancreatic Cancer

IL-6 Secreted from Pancreatic Stellate Cells Activates STAT3 and Promotes Cell Growth and Invasive Ability of Pancreatic Cancer

Posted by Printess Berry on Thursday, October 15th, 2015 in May 2014, , ,

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Genetic Diversity Among Mitochondrial Genes of Daucus carota

The quantitative genetic diversity of select mitochondrial genes and population structure of Daucus carota populations was studied.

Posted by Printess Berry on Tuesday, September 15th, 2015 in May 2011, , , ,

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The Effects of Tachykinin on Olfactory Reception in Periplaneta americana

A neuropeptide found in invertebrates, the tachykinin-related peptide, caused an overall decrease in olfactory sensitivity for the American cockroach.

Posted by Printess Berry on Tuesday, September 15th, 2015 in May 2011, , , , , ,

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The Effect of Pyrvinium, a Potent Small Molecule Wnt Inhibitor, on MSC Biology

Inhibition of the Wnt signaling pathway promotes favorable tissue regeneration and remodeling.

Posted by Printess Berry on Tuesday, September 15th, 2015 in May 2011, , ,

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Schizophrenia and the Potentiation of the Postauricular Refl ex: A Study on Emotion

This study focused on the emotional perception of schizophrenic patients, using a biological method.

Posted by Printess Berry on Thursday, August 27th, 2015 in May 2012, , ,

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Development of an Intelligent, Real-time, Heart Rate Sensitive Virtual Reality System

A real-time analysis of the anxiety level of a subject was predicted by a virtual reality system based on the subject’s heart rate

Posted by Printess Berry on Thursday, August 27th, 2015 in May 2012, , , ,

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Freestanding Carbon Nanotube Films Fabricated By Post-Electrophoretic Deposition Electrochemical Separation

The development of a novel method for producing buckypapers following electrophoretic deposition of carbon nanotubes is presented.

Posted by Printess Berry on Thursday, August 27th, 2015 in May 2012, , , ,

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Consequences of Altering Transforming Growth Factor Beta Receptor Type III (TβRIII) Expression in the Prostate

The goal of this study was to observe how changing the expression of TβRIII affects prostate cancer progression.

Posted by Printess Berry on Thursday, August 27th, 2015 in May 2012, , , , , ,

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Optimizing Transfection Efficiency and Determining Release Kinetics of Plasmid DNA from Polyurethane Scaff olds in vitro

The purpose of this study was to deliver DNA from biomaterial scaffolds to cells in vitro.

Posted by Printess Berry on Thursday, August 27th, 2015 in May 2012, , , ,

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Identification of Novel Helicobacter pylori Adhesins that Bind the Host Cell Receptor Decay-Accelerating Factor (DAF)

H. pylori adherence is critical for gastric cancer development, and this study has identifi ed novel adhesins responsible for DAF-mediated adherence.

Posted by Printess Berry on Thursday, August 27th, 2015 in May 2012, , ,

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