May 2021 Issue
Anaphylaxis Alert: An affordable, wearable health monitoring device
Wearable technology providing continuous monitoring of oxygen saturation levels for the detection of anaphylactic shock.
Posted by John Lee on Thursday, May 20th, 2021 in May 2021, Anaphylaxis, Medical Device, Wearable Technology
Breast Cancer Metastasis to the Bone Microenvironment
A majority of breast cancer patients develop metastases in their bone, and the bone microenvironment plays a large role in recruiting tumor cells from the breast.
Posted by John Lee on Thursday, May 20th, 2021 in May 2021, adipocytes, bone metastasis, breast cancer, stiffness
The Effect of Microplastic Pollution on Symbiotic Bacteria within the Marine Sponge, Halichondria panicea
This research looks at the effect microplastic pollution can have on the viability of symbiotic bacteria within the main sponge, Hali-chondria panicea, to understand if future pharmaceutical discoveries derived from preexisting antibacterial compounds may be limited.
Posted by John Lee on Thursday, May 20th, 2021 in May 2021, Marine Biology, Marine Sponges, Microplastics, Symbiotic Bacteria
The Stereo Camera – A Cost-Efficient User Controlled Medical Instrument for Ophthalmic Use
The prototype designed is a stereoscopic camera system utilizing cheap yet effective materials such as the Raspberry Pi and its respective camera modules, along with custom 3D printed adapters.
Posted by John Lee on Thursday, May 20th, 2021 in May 2021, Affordability, Ophthalmology, Stereoscopy, Technology
Global Patent Landscape of Induced Pluripotent Stem Cells
Review and analysis of worldwide patent literature regarding induced pluripotent stem cells.
Posted by John Lee on Thursday, May 20th, 2021 in May 2021, induced pluripotent stem cells, Intellectual Property, iPSC, Patent Landscape
Liposome-based Strategies to Mitigate Ischemic Stroke-induced Neurodegeneration
Liposome-based drug delivery to the brain is a well-established and an effective approach for delivering neuroprotectants across the BBB in ischemic stroke.
Posted by John Lee on Thursday, May 20th, 2021 in May 2021, Blood Brain Barrier, Drug Delivery Systems, Liposomes, Stroke
The Rise of Allergies: An Investigation on Why It Is Occurring and How to Stop It
This paper analyzes correlations between the presence of allergies and various childhood and adult lifestyle factors of 70 participants.
Posted by John Lee on Thursday, May 20th, 2021 in May 2021, Allergies, Allergy, Anaphylaxis, Rhinitis
Comparing a Survivin Inhibitor to Carboplatin for Treating Small Cell Lung Cancer in vitro
We find inhibition of survivin using YM155 to be more potent (lower-dose requirements) than the traditional, platinum-based chemo-therapy carboplatin with the same maximal efficacy (loss of cell-viability) when treating small cell lung cancer cells in vitro.
Posted by John Lee on Thursday, May 20th, 2021 in May 2021, chemotherapy, Small Cell Lung Cancer, Survivin, YM155
Nuclear Virus-Host Interactions During Coronavirus Infection
Despite replicating in the cytoplasm, coronaviruses employ several mechanisms surrounding the nucleus to promote proliferation.
Posted by John Lee on Thursday, May 20th, 2021 in May 2021, Coronavirus, Gene Regulation, Nuclear Transport, Nucleolus, Nucleus
Adipose Tissue Macrophage Transcriptome Suggests Trained Innate Immunity Formation in Response to Weight Cycling
Single cell sequencing suggests evidence of trained innate immunity in adipose tissue macrophages from weight cycled mice.
Posted by John Lee on Thursday, May 20th, 2021 in May 2021, Adipose tissue macrophages, Obesity, trained innate immunity, weight cycling
The Design and Modification of an Innovative Loofah Sponge Device for the Removal of Aquatic Microplastics
A device consisting of a loofah vessel with hair inside is used to effectively remove microplastics from water.
Posted by John Lee on Wednesday, May 19th, 2021 in May 2021, Environmental Science, Hair, Loofah, Microplastics
The Biological Concepts and Treatment Therapies of Rhabdoid Tumors
This review will explore the biology behind rhabdoid tumors and current/potential future treatment therapies.
Posted by John Lee on Wednesday, May 19th, 2021 in May 2021, AT/RT, MRT, Rhabdoid Tumors
Removing Dark Region Artifacts using Deep Neural Networks with a Hyperparameter Search
This study used deep neural networks to remove dark region artifacts in order to create clearer ultrasound images.
Posted by John Lee on Wednesday, May 19th, 2021 in May 2021, Deep Neural Network, Machine learning, Ultrasound