Identification and Characterization of Helicobacter pylori Genes Regulating DNA Translocation and TLR9 Activation by the Cancer-Associated cag Type IV Secretion System
Novel Helicobacter pylori genes regulating DNA translocation and TLR9 activation were identified and characterized to investigate the role of DNA translocation in gastric cancer development.
Posted by John Lee on Tuesday, December 22nd, 2020 in May 2019, cancer, gastric, Helicobacter, pylori, TLR9
Building a Konstanz Information Miner (KNIME) pipeline to assess the utility of immunofluorescence computational analysis of ALCAM in bladder cancer
A KNIME pipeline for performing single-cell, multiplex immunofluorescence
Posted by John Lee on Tuesday, December 22nd, 2020 in May 2018, ALCAM, bladder cancer, KNIME, single-cell analysis
SPRR3 Regulates the Cooperative Signaling of Integrins and Growth Factor Receptors to Modulate Cardiac Fibrosis
The SPRR3 protein does not affect individual integrin function in fibroblasts, supporting that SPRR3 influences the cooperative signaling of integrins and growth factor receptors.
Posted by John Lee on Tuesday, December 22nd, 2020 in May 2018, Fibroblast, Growth Factor Receptor, Heart Failure, Integrin, SPRR3 protein
Gli2 Regulation of Parathyroid Hormone-Related Protein Expression in Metastatic Breast Cancers
Four variations of the PTHrP promoter were tested to determine which yielded the highest PTHrP expression in order to discern which region is most important for Gli2 activation of PTHrP in Tumor-Induced Bone Disease.
Posted by John Lee on Tuesday, December 22nd, 2020 in May 2018, Gli2, Metastatic Breast Cancer, Promoter, PTHrP, Tumor-Induced Bone Disease
Simulating Visual Deficits in a Virtual Environment: A Street Crossing Study
Simulating and quantifying the effects of visual deficits in virtual reality will help individuals, such as medical professionals, better under-stand those suffering from visual impairments.
Posted by John Lee on Tuesday, December 22nd, 2020 in May 2018, Computer Science, Macular Degeneration, programming, Virtual reality, Visual Deficits
Resilience Assessment of Power Distribution Systems: Preliminary Data Analysis of the Impact of Power Outages on Communities
Through linear modeling, impacts of natural disasters can be estimated to give decision makers information on the duration of a power outage.
Posted by John Lee on Tuesday, December 22nd, 2020 in May 2018, Linear Modeling, Power Outages, Systems Resilience
Quantifying Young’s Modulus of Gelatin Substrates for in vitro BBB Models
An examination of the effect of gelatin concentration on Young’s Modulus preformed for future in vitro Blood Brain Barrier studies.
Posted by John Lee on Tuesday, December 22nd, 2020 in May 2018, Blood Brain Barrier, in vitro, Young’s Modulus
Concrete Printing System Construction and Characterization of 3-D Printed Cement-based Materials
Cement-based materials were designed and printed on a novel extrusion system, then characterized.
Posted by John Lee on Tuesday, December 22nd, 2020 in May 2018, 3-D Printing, Additive Manufacturing, Cement, Microstructure, Mix Design
The Association between Social Fear and Intrinsic Amygdala Function Is Modulated by Biological Sex
Social fear and intrinsic amygdala function were investigated using the amplitude of low-frequency fluctuations (ALFF) and were found to be moderated by a distinct factor – biological sex.
Posted by John Lee on Tuesday, December 22nd, 2020 in May 2018, ALFF, amygdala, social anxiety disorder, Social fear
An Analysis of Ice Sheet – Ice Shelf Mechanics through Finite Element Models
A 2D computational model of an idealized ice sheet was created and validated to understand the relations between ice sheet-ice shelf geometry and mechanical stress.
Posted by John Lee on Tuesday, December 22nd, 2020 in May 2018, Finite element model, Fracture, Ice sheet, Mechanical stress
The effect of SENSE Theatre as a therapy on language delays in children with Autism Spectrum Disorder
Children with Autism Spectrum Disorder may develop greater language ability following a novel theatre intervention known as SENSE Theatre.
Posted by John Lee on Tuesday, December 22nd, 2020 in May 2018, Autism, Language, SENSE Theatre, Therapy
A Multi-User Collaborative Game Created to Improve Cognitive and Physical Aspects and Socialization Skills of Individuals with Dementia
A multi-user collaborative game was created to improve the socialization skills and cognitive aspects of individuals with dementia.
Posted by John Lee on Tuesday, December 22nd, 2020 in May 2018, Dementia, Razer Hydra, Unity
Crime Prediction and Optimal Police Allocation
In this report, we use the transportation problem, a classical optimization problem, to optimize police allocation and survival analysis to predict crime. By doing this, we minimize the overall response time for police officers.
Posted by John Lee on Tuesday, December 22nd, 2020 in May 2018, Crime prediction, optimization, police allocation
Cortical Evoked Potentials Identify Compensatory Effects of Attention on Auditory Processing in Children and Adults
This study examines the effects of noise, attention, and age on neural processing of speech.
Posted by John Lee on Tuesday, December 22nd, 2020 in May 2018, auditory processing, event-related potentials, N1, Speech-in-noise perception
Development of a Machine Learning Algorithm for the Prediction of Enhancer Region Activity
A machine learning algorithm was programmed and optimized to predict the activity of enhancer regions of DNA.
Posted by John Lee on Tuesday, December 22nd, 2020 in May 2018, algorithm, enhancer, genetics, Machine learning, prediction
Tunable Metamaterials in the Infrared
A tunable metamaterial was realized in the infrared by adding vanadium dioxide to a gold resonator.
Posted by John Lee on Tuesday, December 22nd, 2020 in May 2018, infrared, metamaterial, tunable, vanadium dioxide
Recovery of Putative Temperature-Sensitive Mutations in Coro-navirus Nonstructural Protein 5 Reveals Conserved Determi-nants of nsp5 Structure
This study identifies temperature-sensitive mutations as conserved determinants in coronavirus nsp5 proteins of strains HKU1 and OC43.
Posted by Greta Clinton-Selin on Wednesday, June 28th, 2017 in May 2013, Coronavirus, Nonstructural Protein 5, Temperature-Sensitive Mutations
Using Detrital Zircon Age Distributions to Corroborate Evidence of Early Holocene Megafloods
Zircon grain age distributions provide information on the origins of early holocene megaflood related sediment.
Posted by Greta Clinton-Selin on Thursday, June 8th, 2017 in May 2017, arsenic, Groundwater, Megaflood, Zircon
Development of a Portable and Inexpensive Ultrasound Imaging Device for Use in the Developing World
A portable and inexpensive ultrasound device that could be used in the developing world was developed and tested.
Posted by Greta Clinton-Selin on Thursday, June 8th, 2017 in May 2017, BeagleBone, Phantom, Portable, Ultrasound
Bulk Mechanical Characterization of Nanoparticle Concrete-Equivalent Mortars
Ultimate concrete strength was studied as a factor of both mass and surface area of nanoparticles added to the material.
Posted by Greta Clinton-Selin on Wednesday, June 7th, 2017 in May 2017, compressive strength, concrete, mass, Nanoparticles, nuclear waste storage, surface area
An Analysis on the Impact of Peer-Mediated Theatre Interventions for Children with Autism on Typically Developing Peers
The analysis of changes in model peers during behavioral interventions designed for children with Autism Spectrum Disorder.
Posted by Greta Clinton-Selin on Monday, June 5th, 2017 in May 2017, Behavioral Intervention, Peer-Study, Salivary Cortisol
Stable Isotope and Dental Microwear Ecology of the Arid Adapted Red Kangaroo (Macropus rufus)
Analysis of the relationship between climate, isotopes, and dental microwear for the red kangaroo.
Posted by Greta Clinton-Selin on Friday, June 2nd, 2017 in May 2017, aridity, climate, diet, microwear, Stable isotopes
Analyzing the Efficacy of Different Gas Chromatography-Mass Spectrometry Methods in Determining Glucose Concentrations
Measuring multiple glucose concentrations using a Gas Chromatography-Mass Spectrometry based technique.
Posted by Greta Clinton-Selin on Thursday, June 1st, 2017 in May 2017, diabetes, Gas-Chromatography-Mass Spectrometry (GC-MS), Glucose Cycling, total ion abundance screening
Creating an Agent-Based Model to Explore the Spread of Zika Virus
Predicted Zika outbreak severity directly correlates with human population density.
Posted by Greta Clinton-Selin on Tuesday, May 30th, 2017 in May 2017, Agent-based modeling, Zika Virus
The Impact of Connective Tissue Growth Factor on Glucose Home-ostasis and Islet Physiology in Virgin and Pregnant Mice
The loss of Connective tissue growth factor (Ctgf) does not affect islet physiology, indicating other existing problems in glucose homeostasis.
Posted by Greta Clinton-Selin on Tuesday, May 30th, 2017 in May 2017, Connective Tissue Growth Factor (Ctgf), diabetes, glucose, Islet, Physiology
Accuracy of Resting Functional MRI for Language Lateralization in Temporal Lobe Epilepsy
Method development for language lateralization using resting-state fMRI scans in temporal lobe epilepsy patients.
Posted by Greta Clinton-Selin on Thursday, May 25th, 2017 in May 2017, Language Lateralization, Resting fMRI, Temporal Lobe Epilepsy
Analyzing Phospho-signaling in Human Glioblastoma Cell Lines Using Ex Vivo Culture
Phospho-protein activation was highest at the edges of organoids grown from glioblastoma cell lines, which may indicate key locations for potential treatment targets.
Posted by Greta Clinton-Selin on Thursday, May 25th, 2017 in May 2017, cancer, Epidermal Growth Factor Receptor (EGFR), Glioblastoma, Organoid, phospho-protein activation
Development of Withdrawal Algorithm for Capsule Endoscopy in Research and Clinical Setting
An algorithm was developed to autonomously control the capsule endoscope, allowing doctor to focus on diagnosing the patient.
Posted by Greta Clinton-Selin on Wednesday, May 24th, 2017 in May 2017, Endoscopy, external magnet, nanotechnology, python, simulation
POPDC3 Regulates Epithelial-Mesenchymal-Transition in Colorectal Cancer Cells
The POPDC3 protein was identified as a potential regulator of the epithelial-mesenchymal-transition process in colorectal cancer.
Posted by Greta Clinton-Selin on Wednesday, May 24th, 2017 in May 2017, colorectal cancer, epithelial-mesenchymal transition, Popdc3
Characterization of the Downstream Effects of Apical Mistrafficking of Epiregulin and Potential for Transformation in Polarized Epithelial Cells
Loss of epithelial polarity and mistrafficking of Epiregulin may be a driving force for cancer in polarized epithelial cells.
Posted by Greta Clinton-Selin on Wednesday, June 29th, 2016 in May 2016, Apical, Basolateral, cancer, Epiregulin (EREG), Trafficking
Classification of Infant Cries Using Acoustic Features
Identifying an acoustic feature combination that can accurately differentiate between infant cries.
Posted by Greta Clinton-Selin on Wednesday, June 29th, 2016 in May 2016, classification, cries, features, Matlab, NICU, pain
Determining the Turning Wing Kinematics of a Ruby-Throated Hummingbird
The turning wing kinematics of a ruby-throated hummingbird are determined by use of a blade element model.
Posted by Greta Clinton-Selin on Wednesday, June 8th, 2016 in May 2016, blade element model, computational fluid dynamics, Micro Aerial Vehicles
Improving Patterned Nanoporous Gold as an Effective Surface Enhanced Raman Scattering Template
An imprinted nanoporous gold substrate was optimized to create a low power Raman biological and chemical sensor.
Posted by Greta Clinton-Selin on Tuesday, June 7th, 2016 in May 2016,
Measuring the degradation of robot components caused by gamma radiation.
Individual component radiation testing is an effective way to gather data for the development of modeling software to predict a system's radiation response.
Posted by Greta Clinton-Selin on Friday, June 3rd, 2016 in May 2016, Bayesian Network model, Gamma radiation, Pololu robot
Obesity Contributes to an Accumulation of Ly6chigh Pro-inflammatory Monocytes in the Spleen and White Adipose Tissue
The purpose of this experiment was to see whether or not obesity correlated with an increase in pro-inflammatory monocytes
Posted by Greta Clinton-Selin on Friday, June 3rd, 2016 in May 2016, Immune System, Immunology, Monocytes, Obesity
Assessment of Hedgehog/GLI2 signaling inhibitors within metastatic breast cancers
Hedgehog pathway inhibitors were established as potential remediation treatments for tumor-induced bone disease. Additionally, hypotheses concerning inhibition methods were established for future investigation.
Posted by Greta Clinton-Selin on Friday, June 3rd, 2016 in May 2016, Gli2, Hedgehog Pathway Inhibitor, Metastatic Breast Cancer, PTHrP
Regulation of Pro-Inflammatory Phenotypes by Carcinogenic and Non-Carcinogenic Helicobacter pylori strains
In order to quantify H. pylori virulence, the concentration of IL-8 secreted by AGS gastric epithelial cells co-culture with H. pylori strains, isolated from patients with gastritis or gastric adenocarcinoma was measured and compared.
Posted by Greta Clinton-Selin on Thursday, June 2nd, 2016 in May 2016, gastric cancer, gastritis, Helicobacter pylori, Interleukin-8
Constructing Mobile Device Application to Interact with Modular Robotics Toolkit over Bluetooth®
This work develops a Bluetooth phone application to control a modular robotic toolkit using an open source environment.
Posted by Greta Clinton-Selin on Tuesday, May 24th, 2016 in May 2016, Atmosphere Anaren, Bluetooth, MCRs, open source, phone application
Effects of Ozone Plasma Treatment and X-Ray Irradiation on Optical Properties of Atomically Thin Molybdenum Disulfide
Effects of Ozone Plasma Treatment and X-Ray Irradiation on Optical Properties of Atomically Thin Molybdenum Disulfide
Posted by Printess Berry on Thursday, October 15th, 2015 in May 2014, materials characterization, MoS2, nanotechnology
Explicit Phonemic Awareness of Adolescents: Skills at Baseline and Following Brief Instruction
Explicit Phonemic Awareness of Adolescents: Skills at Baseline and Following Brief Instruction
Posted by Printess Berry on Thursday, October 15th, 2015 in May 2014, high school, literacy, Phonemic awareness
The Effects of CTGF Overexpression on β-Cell Regeneration and Survival
The Effects of CTGF Overexpression on β-Cell Regeneration and Survival
Posted by Printess Berry on Tuesday, October 13th, 2015 in May 2014, CTGF, diabetes, β-cell regeneration
Functional Dissection of the Central Domain of c-Myc through Characterization of Novel Interacting Proteins
Authors: Ranine A. Haidous and William P. Tansey
Posted by Printess Berry on Tuesday, August 25th, 2015 in May 2013, c-Myc, cancer, yeast two-hybrid assay
Perceived Barriers and Facilitators to HPV Vaccination in African American Girls Ages 11–18
Authors: Melenka B. Reed, Maureen Sanderson, Elizabeth A. Williams and Pamela C. Hull
Posted by Printess Berry on Tuesday, August 25th, 2015 in May 2013, African American, cervical cancer, HPV, Human papilloma virus