‘Immunotherapy’
GITR-Targeted Small Molecules for Cancer Immunotherapy
A computational investigation identifying and evaluating potential small-molecule binding sites on the GITR protein to inform immunotherapy strategies.
Posted by buchanle on Wednesday, May 20th, 2026 in May 2026, cancer, Drug Discovery, GITR, immune checkpoints, Immunotherapy
Regulation of the PPARꝩ Pathway using Antagonists and In-verse Agonists across 2D and 3D Models
Utilizing the peroxisome proliferator-activated receptor gamma pathway (PPARꝩ) for immunotherapy in lung cancer models.
Posted by buchanle on Friday, May 15th, 2026 in May 2026, Immunotherapy, inhibition, lung cancer, Proliferation
Encapsulating Synthetic STING Agonist, MSA-2, in Endosomolytic Polymersomes for Cancer Immunotherapy
Utilization of STING agonist MSA-2 encapsulated nanocarriers to enhance the immune system’s ability to eliminate cancer cells.
Posted by buchanle on Wednesday, June 25th, 2025 in May 2025, cancer, Flash nanoprecipitation, Immunotherapy, MSA-2, Nanocarrier, STING
Synthesis and Characterization of Macromolecular Polymeric STING Agonists for Cancer Immunotherapy Applications
Incorporating STING agonists into polymeric delivery systems as an alternative cancer treatment.
Posted by buchanle on Tuesday, April 30th, 2024 in May 2024, Agonist, Immunotherapy, Nanoparticle, polymer