Crowdsourced Ligand Design for Selective Inhibition of the KNa1.2 (Slick) Potassium Channel implicated in Developmental Epileptic Encephalopathies

A hybrid strategy of small molecule drug design that combined evolutionary and crowd sourced designs yielded novel synthetically accessible candidate inhibitors of the Kna1.2 channel implicated in developmental epileptic encephalopathies.

Posted by buchanle on Monday, May 18th, 2026 in May 2026, Foldit, KCNT2, KNa1.2, Ligand, REvoLd

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