Computational Simulations of Bispecific Aptamers Targeting CD16+ Natural Killer Cells and PD-L1+ Cancer Cells
A computational study exploring the design of bispecific aptamers to enhance NK cell-mediated cancer therapy through targeted receptor interactions.
Posted by buchanle on Friday, June 20th, 2025 in May 2025, Aptamer, CAR T-cell Therapy, Molecular Docking, NK Cells
Computation simulations of IL-13Rα2 receptor+ CAR T-cell targeting high-grade glioma
This work uses computer simulations to investigate the interactions between CAR T-cells expressing CD45 and CD62 receptors and the IL-13Rα2 receptor, offering insights into the best way to target high-grade gliomas using CAR T-cell therapy.
Posted by buchanle on Thursday, June 19th, 2025 in May 2025, CAR T-cell Therapy, Glioma, Molecular Docking, Molecular Dynamics