Effect of Antisense Oligonucleotides on the Expression Level of Human Progranulin Associated with Frontotemporal Dementia
Using ASOs to compete for the miR-29b’s binding site leads to higher levels of progranulin, which would treat frontotemporal dementia caused by progranulin-deficiency.
Posted by John Lee on Saturday, May 7th, 2022 in May 2022, Antisense Oligonucleotides, FTD, miR-29b, Progranulin