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Rizzo Laboratory

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Chem 224: Bioorganic ChemistryBibliography and Suggested Reading 

Amino Acid and Peptide Chemistry:

  • Fmoc Solid Phase Peptide Synthesis: A Practical Approach, W. C. Chan and P. D. White, Eds., Oxford University Press. New York, 2000.
  • Chemistry of Peptide Synthesis, N. Leo Benoiton, CRC Press, Boca Raton, 2005.
  • Peptide Chemistry. A Practical Textbook, 2nd ed., Miklos Bodanszky, Springer-Verlarg, Berlin, 1993.
  • Principles of Peptide Synthesis, 2nd ed., Miklos Bodanszky, Springer-Verlarg, Berlin, 1993.
  • Chemical Approaches to the Synthesis of Peptides and Proteins, P. Lloyd-Williams, F. Albericio, E. Giralt, CRC Press, Boca Raton ,1997.
  • “Total Chemical Synthesis of Proteins.” Fitzgerald, M. C.; Kent, S. B. H., In Bioorganic Chemistry: Peptides and Proteins, S. M. Hecht, Ed., Oxford Press, Oxford, 1998, pp. 65-99.
  • “Chemical Protein Synthesis.” Wilken, J.; Kent, S. B. H. Curr. Opin. Biotechnol. 1998, 9, 412-426.
  • “Chemical Synthesis of Proteins.” Nilsson, B. L.; Soellner, M. B. ; Raines, R. T. Annu. Rev. Biophys. Biomol. Struct. 2005, 34, 91-118.
  • “Synthesis of Native Proteins by Chemical Ligation.” Dawson, P. E.; Kent, S. B. H. Annu. Rev. Biochem. 2000, 69, 923-960.

Mass Spectroscopy of Peptides:

  • Introduction to Proteomics: Tools for the New Biology, Liebler, D. C., Human Press: 2002.
  • “Mass Spectoscopy of Peptides and Proteins.” Biemann, K. Annu. Rev. Biochem. 1992, 61, 977-1010.
  • “Overview of Peptide and Protein Analysis by Mass Spectrometry,” Carr, S. A.; Annan, R. S. Curr. Protoc. Protein Sci. 2001 Chapter 16:Unit 16.1.

Combinatorial Chemistry:

  • Combinatorial Chemistry, Nicholas K. Terrett, Oxford University Press, London, 1998
  • “Synthesis and Applications of Small Molecule Libraries.” Thompson, L. A.; Ellman, J. A. Chem. Rev. 1996, 96, 555-600.
  • “Design, Synthesis, and Evaluation of Small-Molecule Libraries.” Ellman, J. A. Acc. Chem. Res. 1996, 29, 132 -143.
  • “Application of Combinatorial Technologies to Drug Discovery. 1. Background and Peptide Combinatorial Libraries.” Gallop, M. A.; Barrett, R. W.; Fodor, S. P. A.; Gordon, E. M. J. Med. Chem. 1994, 37, 1233-1251.
  • “Application of Combinatorial Technologies to Drug Discovery. 2. Combinatorial Organic Synthesis, Library Screening Strategies, and Future Directions.” Gordon, E. M.; Barrett, R. W.; Fodor, S. P. A.; Gallop, M. A. J. Med. Chem. 1994, 37, 1386-1401.

Peptidomimetics:

  • “Concepts and Progress in the Development of Peptide Mimetics.” Olson, G. L. et al. J. Med. Chem. 1993, 36, 3039-3049.
  • “Peptide Mimetics.” Nakanishi, H.; Kahn, M., In Bioorganic Chemistry: Peptides and Proteins, S. M. Hecht, Ed., Oxford Press, Oxford, 1998, pp. 395-419.
  • “Peptidomimetics for Receptor Ligands- Discovery, Development, and Medical Perspectives.” Giannis, A.; Kolter, T. Angew. Chem. Int. Ed. Engl. 1993, 32, 1244-1267.

De Novo Protein Design

  • “De Novo Design and Structural Characterization of Proteins and Metalloproteins.” DeGrado, W. F.; Summa, C. M.; Pavone, V.; Nastri, F.; Lombardi, A. Annu. Rev. Biochem. 1999, 68, 779-819.

Enzyme and Cofactor Chemistry

  • An Introduction to Enzyme and Coenzyme Chemistry ,Tim Bugg, Blackwell Science, Oxford, 1997
  • The Organic Chemistry of Enzyme-Catalyzed Reactions, Richard J. Silverman, Academic Press, NY, 2000
  • Enzymatic Reaction Mechanisms, Christopher Walsh, W. H. Freeman, San Francisco, 1979
  • The Organic Chemistry of Biological Pathways, J. McMurry and T. Begley, Roberts & Company Publishers, Colorado, 2005.

Nucleic Acid Chemistry

  • Nucleic Acids in Chemistry and Biology, Blackburn, G. M.; Gait, M. J., Loakes, D., Williams, D., Eds., Royal Society of Chemistry Publishing, England, 2006
  • Bioorganic Chemistry: Nucleic Acids, S. M. Hecht, Ed., Oxford Press, Oxford, 1998
  • The Biochemistry of the Nucleic Acids, Adams, R. L. P.; Knowler, J. T.; Leader, D. P., Chapman & Hall, London, 1992
  • Principles of Nucleic Acid Structure, W. Saenger, Springer-Velag, Berlin, 1984
  • “Synthesis of Nucleosides,” Vorbruggen, H.; Ruh-Pohlenz Organic Reactions 2000, 55, 1-630.

Antisense and Antigene Oligonucleotides

  • “The New Genetic Medicines.” Cohen, J. S.; Hogan, M. E. Scientific American 1994 (December issue), p 76.
  • “Antisense/Antigene Oligonucleotides,” Miller, P. S., Bioorganic Chemistry: Nucleic Acids, S. M. Hecht, Ed., Oxford Press, Oxford, 1998, pp 347-374.

Natural Products Biosysnthesis

  • Chemical Aspects of Biosysnthesis, John Mann, Oxford Science Publications: London, 1994.